Advances in tumor subclone formation and mechanisms of growth and invasion

Abstract Tumor subclones refer to distinct cell populations within the same tumor that possess different genetic characteristics. They play a crucial role in understanding tumor heterogeneity, evolution, and therapeutic resistance. The formation of tumor subclones is driven by several key mechanisms...

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Bibliographic Details
Main Authors: Yuhong Zhang, Weidong Wang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06486-3
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