The phenotypic characterization of mouse floxed Fam20b chondrocytes, a novel articular cartilage-derived cell line with differentiation potential

FAM20B is a newly identified kinase involved in proteoglycan biosynthesis. Inactivation of Fam20b in joint cartilage leads to chondrosarcoma. Generation of chondrocytes cell line carrying floxed Fam20b allele can offer a valuable tool for the study of the role of Fam20b as well as the molecular even...

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Bibliographic Details
Main Authors: Xiaoyuan Wu, Lei Zhu, Lifeng Xia, Lin Gui, Wei Cong
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Regenerative Therapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S235232042500029X
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