Does KarXT (xanomeline-trospium) represent a novel approach to schizophrenia management? A GRADE-assessed systematic review and meta-analysis of randomized controlled clinical trials

Abstract Background Schizophrenia is a complex psychiatric disorder characterized by positive, negative, and cognitive symptoms. KarXT, a novel combination of xanomeline and trospium, offers potential therapeutic benefits for schizophrenia treatment by targeting muscarinic receptors and avoiding dop...

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Bibliographic Details
Main Authors: Hazem E. Mohammed, Menna A. Gomaa, Youssef Magdy Khalifa, Ahmed Ayman Shawky
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-025-06696-5
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