Diagnosing malignant transformation potential in oral submucous fibrosis with leukoplakia: an approach utilizing deoxyribonucleic acid image cytometry

Diagnosing malignant transformation potential in oral submucous fibrosis with leukoplakia: an approach utilizing deoxyribonucleic acid image cytometry

Abstract Oral submucous fibrosis (OSF) is a chronic oral condition with a potential for malignant transformation. This study aims to investigate the correlation between DNA aneuploidy and dysproliferative lesions in OSF using DNA image cytometry to provide insights into cancer risk assessment. The s...

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Bibliographic Details
Main Authors: Huan Li, Wenhui Li, Liming He, Wenhui Ge, Yi Yu, Jiaming Lin, Shuangjiang Li, Xiaoyan Xie, Tianyou Ling
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
DNA image cytometry
Oral submucous fibrosis
Oral leukoplakia
Oral squamous cell carcinoma
Epithelial dysplasia
Online Access:https://doi.org/10.1038/s41598-025-05870-9
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https://doi.org/10.1038/s41598-025-05870-9

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