Therapeutic time window of sodium of Danshensu on cerebral ischemia and its mechanism of inhibiting oxidative stress and ferroptosis through Nrf2 pathway

Background: Sodium of Danshensu (SDSS), extract of salvia miltiorrhiza root, has been shown to have neuroprotective effects on ischemic stroke (IS) in our previous studies. However, its therapeutic time window and mechanism of action remain unclear. Ferroptosis exerts a crucial feature in the develo...

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Bibliographic Details
Main Authors: Chao Guo, Zhongying Ma, Xingru Tao, Kai Gao, Wei Zhang, Aidong Wen, Yi Ding, Jingwen Wang
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Brain Research Bulletin
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Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025002084
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