Transmission cluster of cefiderocol-non-susceptible carbapenem-resistant Acinetobacter baumannii in cefiderocol-naïve individuals

Transmission cluster of cefiderocol-non-susceptible carbapenem-resistant Acinetobacter baumannii in cefiderocol-naïve individuals

Abstract Background During prolonged FDC therapy, the emergence of FDC non-susceptibility in CRAB has been reported. Here, we report a transmission cluster of FDC-non-susceptible CRAB in four patients, all naïve to FDC treatment, characterized by a premature stop codon and amino acid deletion in the...

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Main Authors: Claudia Alteri, Antonio Teri, Maria Francesca Liporace, Antonio Muscatello, Leonardo Terranova, Margherita Carnevale Schianca, Federica Salari, Beatrice Silvia Orena, Flaminia Gentiloni Silverj, Mara Bernazzani, Simona Biscarini, Giulia Renisi, Lisa Cariani, Caterina Matinato, Ciro Canetta, Alessandra Bandera, Annapaola Callegaro
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Healthcare-associated infections
CRAB
Antimicrobial resistance
ESKAPEs
Surveillance
Cefiderocol
Online Access:https://doi.org/10.1186/s12941-024-00763-7
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https://doi.org/10.1186/s12941-024-00763-7

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