Histones Methyltransferase NSD3 Inhibits Lung Adenocarcinoma Glycolysis Through Interacting with PPP1CB to Decrease STAT3 Signaling Pathway

Histones Methyltransferase NSD3 Inhibits Lung Adenocarcinoma Glycolysis Through Interacting with PPP1CB to Decrease STAT3 Signaling Pathway

Abstract Histones methyltransferase NSD3 targeting H3K36 is frequently disordered and mutant in various cancers, while the function of NSD3 during cancer initiation and progression remains unclear. In this study, it is proved that downregulated level of NSD3 is linked to clinical features and poor s...

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Main Authors: Yanling Zhou, Xintong Peng, Cheng Fang, Xin Peng, Jianing Tang, Zuli Wang, Yao Long, Jielin Chen, Yuanhao Peng, Zewen Zhang, Yanmin Zhou, Jun Tang, Jingzhong Liao, Desheng Xiao, Yongguang Tao, Ying Shi, Shuang Liu
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Advanced Science
Subjects:
glycolysis
histones methyltransferase
lung adenocarcinoma
STAT3 signaling pathway
Online Access:https://doi.org/10.1002/advs.202400381
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https://doi.org/10.1002/advs.202400381

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