Components of Mineralocorticoid Receptor System in Human DRG Neurons Co-Expressing Pain-Signaling Molecules: Implications for Nociception

Components of Mineralocorticoid Receptor System in Human DRG Neurons Co-Expressing Pain-Signaling Molecules: Implications for Nociception

The mineralocorticoid receptor (MR), traditionally associated with renal function, has also been identified in various extrarenal tissues, including the heart, brain, and dorsal root ganglion (DRG) neurons in rodents. Previous studies suggest a role for the MR in modulating peripheral nociception, w...

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Main Authors: Shaaban A. Mousa, Xueqi Hong, Elsayed Y. Metwally, Sascha Tafelski, Jan David Wandrey, Jörg Piontek, Sascha Treskatsch, Michael Schäfer, Mohammed Shaqura
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
corticosteroid receptors
aldosterone synthase
pain signaling molecules
peripheral sensory neurons
pain
human
Online Access:https://www.mdpi.com/2073-4409/14/15/1142
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