Synthesis of U-theraphotoxin-Pv1a_1, an Aedes aegypti larvicidal disulfide bridged peptide from the Colombian tarantula Pamphobeteus verdolaga (Araneae: Theraphosidae)

The attention to the increased resistance of Aedes aegipty to traditional insecticides has been directed to the development of bioinsecticides, such as those produced by insect predators, e.g. spiders. Here we present the solid-phase synthesis of native U-theraphotoxin-Pv1a_1 (n-Pv1a_1) from Pamphob...

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Bibliographic Details
Main Authors: Sebastián Estrada-Gómez, Cristian Salinas-Restrepo, Leidy Johana Vargas-Muñoz, Fanny Guzmán, Cesar Segura, Davinia Pla, Libia Sanz, Juan J Calvete
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Toxicon: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590171025000116
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