Evolocumab Reduces Oxidative Stress and Lipid Peroxidation in Obese Zucker Rats

Evolocumab Reduces Oxidative Stress and Lipid Peroxidation in Obese Zucker Rats

<b>Background/Objectives</b>: Evolocumab inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9) binding to low-density lipoprotein (LDL) receptors, thus allowing more LDL receptors to remove LDL cholesterol from the blood. We aimed to determine the effects of evolocumab on the pl...

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Bibliographic Details
Main Authors: Martina Cebova, Radoslava Bulkova, Olga Pechanova
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pathophysiology
Subjects:
PCSK9
evolocumab
hyperlipidemia
LDL cholesterol
oxidative stress
lipid peroxidation
Online Access:https://www.mdpi.com/1873-149X/32/1/5
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