A case report of successful treatment of advanced thymic squamous cell carcinoma with poor performance status using multimodal therapy

A case report of successful treatment of advanced thymic squamous cell carcinoma with poor performance status using multimodal therapy

Thymic squamous cell carcinoma (TSCC) is a rare yet aggressive tumor associated with a dismal prognosis. The patient, a 76-year-old male, presented with symptoms of fatigue, bloody sputum and dyspnea. Computed tomography (CT) and positron emission tomography/computed tomography (PET/CT) scans demons...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xianhua Xu, Xiang Yan, Yang Qin, Dan Kou, Qi Huang, Qiongcheng Chen, Yejin Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Oncology
Subjects:	thymic squamous cell carcinoma pembrolizumab carboplatin albumin-bound paclitaxel radiotherapy poor PS
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1463772/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Comparison of clinico-pathological characteristics and survival of recurrent ovarian cancer patients on seven different chemo-protocols
by: Sattar Saima, et al.
Published: (2019-03-01)

Phase II trial of nab-paclitaxel plus ramucirumab in combination with nivolumab for unresectable advanced or recurrent gastric cancer after progression on first-line treatment including fluoropyrimidine, platinum, and anti-PD-1/PD-L1 antibody (PADDLE)
by: Hidekazu Hirano, et al.
Published: (2025-02-01)

In Vitro and In Situ Characterization of Fish Thymic Nurse Cells
by: Agust&#237;n G. Zapata, et al.
Published: (1996-01-01)

Pembrolizumab for the Treatment of Locally Advanced Cutaneous Squamous Cell Carcinoma: Patient Selection and Special Considerations
by: Stewart M, et al.
Published: (2025-02-01)

Genetic Variations Affect Chemotherapy Outcomes: A Role of the Spindle-assembly Checkpoint
by: Sinjini Sarkar, et al.
Published: (2024-04-01)

Editorial: Surgical treatment of thymic epithelial tumor and myasthenia gravis
by: Piergiorgio Muriana
Published: (2025-01-01)

An Adult Thymic Stromal-Cell Suspension Model for in Vitro Positive Selection
by: Ann P. Chidgey, et al.
Published: (1998-01-01)

Inter-reader agreement for diagnosing thymic cysts on chest MRI in two tertiary referral centers
by: Yura Ahn, et al.
Published: (2025-02-01)

Metastatic Thymic Mucoepidermoid Carcinoma: The Diagnostic Challenges and Role of CRTC1/MAML2 Translocation in Accurate Diagnosis and Treatment
by: Toshiaki Takahashi, et al.
Published: (2025-01-01)

Pembrolizumab- induced subacute cutaneous lupus erythematosus in a patient with oropharyngeal squamous cell carcinoma: A case report and literature review
by: Beata Mayer, et al.
Published: (2025-12-01)

Antigenic Stimuli do not Influence Thymic B Lymphocytes: A Morphological and Functional Study inGerm-Free and Conventionally Reared Piglets
by: B. Cukrowska, et al.
Published: (1998-01-01)

L-Threonine-Derived Biodegradable Polyurethane Nanoparticles for Sustained Carboplatin Release
by: Seoeun Oh, et al.
Published: (2024-12-01)

Positive Selection by Purified MHC Class II / Thymic Epithelial Cells In Vitro: Costimulatory Signals Mediated by B7 Are Not Involved
by: Eric J. Jenkinson, et al.
Published: (1994-01-01)

Peptide Aptamer–Paclitaxel Conjugates for Tumor Targeted Therapy
by: Xinyang Shen, et al.
Published: (2024-12-01)

Small Flock Poultry Nutrition
by: Michael A. Davis
Published: (2015-11-01)

Avian Diseases Transmissible to Humans
by: Michael A. Davis, et al.
Published: (2015-11-01)

Bobwhite Quail Production
by: Peter A. Skewes, et al.
Published: (2003-07-01)

Classical and Variant Avian Infectious Bronchitis Virus Strains
by: Gary D. Butcher, et al.
Published: (2003-10-01)

Bobwhite Quail Production
by: Peter A. Skewes, et al.
Published: (2003-07-01)

Classical and Variant Avian Infectious Bronchitis Virus Strains
by: Gary D. Butcher, et al.
Published: (2003-10-01)

Small Flock Poultry Nutrition
by: Michael A. Davis
Published: (2015-11-01)

Avian Diseases Transmissible to Humans
by: Michael A. Davis, et al.
Published: (2015-11-01)

Prediction of Poor Outcome Using the Urea to Albumin Ratio in Thoracic Empyema
by: Evgeni Dimitrov, et al.
Published: (2024-05-01)

Examining the Causes of Poor Performance in Primary Schools in Rubanda District
by: Arineitwe, Obadia.
Published: (2025)

“The Poor will always be with you”: Ethical Implications for the Church and Development in Africa
by: Medard, Rugyendo
Published: (2022)

“The Poor will always be with you”: Ethical Implications for the Church and Development in Africa.
by: Rugyendo, Medard
Published: (2024)

Maxillary osteonecrosis linked to Pembrolizumab therapy: a case report
by: Gosselin-Rousselle Louise, et al.
Published: (2024-01-01)

The neutrophil percentage-to-albumin ratio is an independent risk factor for poor prognosis in peritoneal dialysis patients
by: Mingfan Xu, et al.
Published: (2024-12-01)

Recurrent Thymic Carcinoma Treated With Median Sternotomy, Innominate Vein Replacement for Superior Vena Cava, and Iodide Implantation: A Case Report and Review of the Literature
by: Zhong‐zheng Chen, et al.
Published: (2025-01-01)

An Open‐Label Phase II Trial of Pembrolizumab, an Immune Checkpoint Inhibitor Alone or in Combination With Oral Azacitidine as Second‐Line Therapy for Advanced Head and Neck Squamous Cell Cancers
by: Vinod K. Ramani, et al.
Published: (2025-01-01)

Seeking a preferential option for the rural poor in Chile
by: Edward Dew
Published: (2006-01-01)

Transformation of Undifferentiated Thy-1lo B220+ Thymic Lymphoid Cells by the Abelson Murine Leukemia Virus
by: Eric Y. Chen, et al.
Published: (2000-01-01)

K21-Antigen: A Molecule Shared by the Microenvironments of the Human Thymus and Germinal Centers
by: Nesrina Imami, et al.
Published: (1998-01-01)

The Effects of Poor Garbage Disposal Community Health: A Case Study of Kisoro Town Council Kisoro District
by: John, Bizimana
Published: (2019)

Low albumin-to-creatinine ratios (ACR) are associated with poor outcomes in cancer patients
by: Hong Zhao, et al.
Published: (2025-01-01)

Oncological principles in the management of ocular surface squamous neoplasia - A Review
by: Rolika Bansal, et al.
Published: (2025-02-01)

Association between dietary antioxidants, serum albumin/globulin ratio and quality of life in esophageal squamous cell carcinoma patients: a 7-year follow-up study
by: Juwei Zhang, et al.
Published: (2025-01-01)

Expression of CSTF2 in oral squamous cell carcinoma and its relationship with immune infiltration and poor prognosis
by: Zumulaiti Aierken, et al.
Published: (2025-02-01)

Electroacupuncture alleviates paclitaxel-induced peripheral neuropathy by reducing CCL2-mediated macrophage infiltration in sensory ganglia and sciatic nerve
by: Yuanyuan Li, et al.
Published: (2025-01-01)

Carboplatin-resistance-related DNA damage repair prognostic gene signature and its association with immune infiltration in breast cancer
by: Shuwen Dong, et al.
Published: (2025-01-01)