Integrative genomic pan-cancer analysis reveals the prognostic significance of DEFB1 in tumors

Abstract Background Defensin beta 1 (DEFB1) is a key immune response gene, but its role in cancer remains unclear. This study aims to explore DEFB1 expression, genetic alterations, immune infiltration, and prognostic significance across various cancer types. Methods We analyzed DEFB1 expression and...

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Bibliographic Details
Main Authors: Li Wang, Hongyu Yang, Lu Cao, Yang Yang, Ran Ding
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-02340-6
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