Matrix‐Rigidity Cooperates With Biochemical Cues in M2 Macrophage Activation Through Increased Nuclear Deformation and Chromatin Accessibility
Abstract Macrophages encounter a myriad of biochemical and mechanical stimuli across various tissues and pathological contexts. Notably, matrix rigidity has emerged as a pivotal regulator of macrophage activation through mechanotransduction. However, the precise mechanisms underlying the interplay b...
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| Main Authors: | Seung Jae Shin, Buuvee Bayarkhangai, Khaliunsarnai Tsogtbaatar, Meng Yuxuan, Sang‐Hyun Kim, Yong‐Jae Kim, Ali Taghizadeh, Daesan Kim, Dong‐Hwee Kim, Jung‐Hwan Lee, Jeongeun Hyun, Hae‐Won Kim |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-02-01
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| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202403409 |
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