Regulation of STAT5 phosphorylation and interaction with SHP1 by lnc-AC004893, a long non-coding RNA overexpressed in myeloproliferative neoplasms

Regulation of STAT5 phosphorylation and interaction with SHP1 by lnc-AC004893, a long non-coding RNA overexpressed in myeloproliferative neoplasms

Objectives Constitutive activation of Janus kinase 2 (JAK2)/signal transducer and activator of transcription (STAT) signaling pathway is central to the pathogenesis of myeloproliferative neoplasms (MPNs). Long noncoding RNAs (lncRNAs) regulate diverse biological processes. However, the role of lncRN...

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Bibliographic Details
Main Authors: Junjun Yang, Jichen Ruan, Bin Zhou, Sisi Ye, Shenmeng Gao, Xiaoqun Zheng
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Hematology
Subjects:
Myeloproliferative neoplasms
long noncoding RNAs
STAT5
SHP1
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2024.2375045
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https://www.tandfonline.com/doi/10.1080/16078454.2024.2375045

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