Therapeutic JAK inhibition does not impact lung injury during viral or bacterial pneumonia in male mice
Abstract Influenza infections are often complicated by secondary bacterial infections such as MRSA pneumonia, which increase morbidity and mortality. Viral infections lead to an inflammatory response that includes elevated levels of IL‐6 and interferons. IL‐6 activates the JAK/STAT signaling pathway...
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| Main Authors: | Lokesh Sharma, Ravineel B. Singh, Caden Ngeow, Rick van derGeest, Alexis M. Duray, Nathanial J. Tolman, Bryan J. McVerry, Charles S. Dela Cruz, John F. Alcorn, William Bain, Keven M. Robinson |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-02-01
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| Series: | Physiological Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.14814/phy2.70232 |
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