Heparin-Binding Hemagglutinin-Induced Trained Immunity in Macrophages: Implications for Antimycobacterial Defense

Heparin-Binding Hemagglutinin-Induced Trained Immunity in Macrophages: Implications for Antimycobacterial Defense

Tuberculosis (TB) is a major global health threat, with the current <i>Bacillus Calmette–Guérin</i> (BCG) vaccine having limited efficacy against adult pulmonary disease. Trained immunity (TI) is a form of innate immune memory that enhances antimicrobial defense. It is characterized by t...

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Bibliographic Details
Main Authors: Yongqiang Li, Xiuping Jia, Jinhua Tang, Huilian Qiao, Jiani Zhou, Yueyun Ma
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomolecules
Subjects:
heparin-binding hemagglutinin
trained immunity
macrophage
tuberculosis
epigenetic reprogram
Online Access:https://www.mdpi.com/2218-273X/15/7/959
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