Assessment of Favipiravir and Remdesivir in Combination for SARS-CoV-2 Infection in Syrian Golden Hamsters

Assessment of Favipiravir and Remdesivir in Combination for SARS-CoV-2 Infection in Syrian Golden Hamsters

Favipiravir (FVP) and remdesivir (RDV) have demonstrable antiviral activity against SARS-CoV-2. Here, the efficacy of FVP, RDV, and FVP with RDV (FVP + RDV) in combination was assessed in Syrian golden hamsters challenged with SARS-CoV- 2 (B.1.1.7) following intraperitoneal administration. At day 4...

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Main Authors: Megan Neary, Eduardo Gallardo-Toledo, Joanne Sharp, Joanne Herriott, Edyta Kijak, Chloe Bramwell, Helen Cox, Lee Tatham, Helen Box, Paul Curley, Usman Arshad, Rajith K. R. Rajoli, Henry Pertinez, Anthony Valentijn, Shaun H. Pennington, Claire H. Caygill, Rose C. Lopeman, Giancarlo A. Biagini, Anja Kipar, James P. Stewart, Andrew Owen
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Viruses
Subjects:
SARS-CoV-2
favipiravir
remdesivir
combination therapy
Online Access:https://www.mdpi.com/1999-4915/16/12/1838
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