Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair.

Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair.

Jaagsiekte sheep retrovirus (JSRV) is a unique oncogenic virus with distinctive biological properties. JSRV is the only virus causing a naturally occurring lung cancer (ovine pulmonary adenocarcinoma, OPA) and possessing a major structural protein that functions as a dominant oncoprotein. Lung cance...

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Bibliographic Details
Main Authors: Claudio Murgia, Marco Caporale, Ousman Ceesay, Gabriella Di Francesco, Nicola Ferri, Vincenzo Varasano, Marcelo de las Heras, Massimo Palmarini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002014&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002014&type=printable

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