Galactomannan detection in sputum samples of patients with chronic obstructive pulmonary disease: A promising marker for diagnosis of chronic pulmonary aspergillosis?

Galactomannan detection in sputum samples of patients with chronic obstructive pulmonary disease: A promising marker for diagnosis of chronic pulmonary aspergillosis?

Background and purpose: Diagnosing chronic pulmonary aspergillosis (CPA) is challenging due to nonspecific symptoms, variable radiological findings, and limited mycological evidences. While galactomannan (GM) testing has been validated in serum and bronchoalveolar lavage fluid (BAL) for invasive pul...

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Main Authors: Sabrieh Asadi Shahi Sarae, Masoud Aliyali, Vida Mortezaee, Hamidreza Jamaati, Hossein Asgarian Omran, Siavash Abedi, Hossein Mehravaran, Jamshid Yazdani Charati, Maryam Sadat Mirenayat, Mihan Pourabdollah, Kosar Najmi, Sabah Mayahi, Mona Ghazanfari, Ahmed Al-Harrasi, Mahdi Abastabar, Mohammad T. Hedayati, Abdullah M.S. Al Hatmi
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Journal of Infection and Public Health
Subjects:
Galactomannan
Cut-off level
Chronic obstructive pulmonary disease
Chronic pulmonary aspergillosis
Online Access:http://www.sciencedirect.com/science/article/pii/S187603412500139X
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