Case-only analysis in small studies of predictive biomarkers

Abstract Characteristics of tumors and patients can be used as predictive biomarkers to guide treatment choice. Although many potential biomarkers are evaluated each year, only few will eventually be used since evidence is usually based on small studies leading to inconclusive results. Such data are...

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Bibliographic Details
Main Authors: M. Hauptmann, V. H. Nguyen, L. Sollfrank, S. C. Linn, K. Jóźwiak
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-96904-9
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