Novel and legacy per- and polyfluoroalkyl substances in humans: Long-term temporal variability and metabolic perturbations

Novel and legacy per- and polyfluoroalkyl substances in humans: Long-term temporal variability and metabolic perturbations

As legacy per- and polyfluoroalkyl substances (PFAS) are phased out, numerous substitutes have emerged, raising concerns about their potential health impacts. Using targeted and untargeted approaches, we evaluated plasma PFAS on an –omic scale, examining temporal variability and associated metabolom...

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Bibliographic Details
Main Authors: Che-Jung Chang, Anna S. Young, Alexander Keil, Catherine E. Mullins, Donghai Liang, Shanshan Zhao, Dean P. Jones, Xin Hu, Douglas I. Walker, Alexandra J. White
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Environment International
Subjects:
Per- and polyfluoroalkyl substances
Chemical mixtures
Temporal variability
Exposomics
Metabolomics
Untargeted approach
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412025003411
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http://www.sciencedirect.com/science/article/pii/S0160412025003411

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