Generation of an anti-CD5 CAR knock-in human induced pluripotent stem cell line using CRISPR/Cas9 technology
The anti-CD5 chimeric antigen receptor (CAR) is a genetically engineered immune cell therapy developed to target CD5-associated hematologic malignancies, such as T-cell lymphoma and leukemia. Using CRISPR/Cas9-mediated gene targeting, we generated an anti-CD5 CAR knock-in human induced pluripotent s...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | Stem Cell Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506125000819 |
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