53BP1 regulates p53-E2F7-dependent transcriptional gene repression and participates in the Fanconi anemia pathway
Summary: p53-binding protein 1 (53BP1) participates in DNA damage repair through H4K20 di-methylation (H4K20me2)-mediated accumulation at DNA damage sites. However, it remains unclear whether H4K20me2-mediated 53BP1 chromatin binding regulates gene transcription in unstressed cells. Here, we demonst...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | Cell Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124725009234 |
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