Protein meta-functional signatures from combining sequence, structure, evolution, and amino acid property information.
Protein function is mediated by different amino acid residues, both their positions and types, in a protein sequence. Some amino acids are responsible for the stability or overall shape of the protein, playing an indirect role in protein function. Others play a functionally important role as part of...
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| Main Authors: | Kai Wang, Jeremy A Horst, Gong Cheng, David C Nickle, Ram Samudrala |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-09-01
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| Series: | PLoS Computational Biology |
| Online Access: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000181&type=printable |
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