Protein meta-functional signatures from combining sequence, structure, evolution, and amino acid property information.

Protein function is mediated by different amino acid residues, both their positions and types, in a protein sequence. Some amino acids are responsible for the stability or overall shape of the protein, playing an indirect role in protein function. Others play a functionally important role as part of...

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Bibliographic Details
Main Authors: Kai Wang, Jeremy A Horst, Gong Cheng, David C Nickle, Ram Samudrala
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000181&type=printable
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