Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants

Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants

Abstract Preterm infants (<37 weeks’ gestation) are commonly given broad-spectrum antibiotics due to their risk of severe conditions like necrotising enterocolitis and sepsis. However, antibiotics can disrupt early-life gut microbiota development, potentially impairing gut immunity and colonisati...

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Main Authors: Raymond Kiu, Elizabeth M. Darby, Cristina Alcon-Giner, Antia Acuna-Gonzalez, Anny Camargo, Lisa E. Lamberte, Sarah Phillips, Kathleen Sim, Alexander G. Shaw, Paul Clarke, Willem van Schaik, J. Simon Kroll, Lindsay J. Hall
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62584-2
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https://doi.org/10.1038/s41467-025-62584-2

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