Association of MTHFR missense variants with thromboembolic diseases and coagulation factor levels in European populations

Abstract Background Investigations of the association between missense variants in the methylenetetrahydrofolate reductase (MTHFR) gene and thromboembolic diseases have been limited by small sample sizes. The effect of these variants on coagulation factor levels remains similarly uncertain. Objectiv...

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Bibliographic Details
Main Authors: Iyas Daghlas, Mengmeng Wang, Dipender Gill
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Thrombosis Journal
Subjects:
Online Access:https://doi.org/10.1186/s12959-025-00711-1
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