Semaglutide to remodel mitochondrial dynamics and mitophagy balance for vascular dementia therapy

Semaglutide to remodel mitochondrial dynamics and mitophagy balance for vascular dementia therapy

Abstract Vascular dementia (VaD) is a syndrome of cognitive dysfunction caused by cerebrovascular damage. At present, VaD is mainly prevented by controlling vascular risk factors clinically, while there has been limited progress in therapies directly targeting its pathological mechanism. Mitochondri...

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Bibliographic Details
Main Authors: Xiaoyan Yang, Peng Feng, Hongxu Zhu, Mingkang Wang, Nan Li, Bo Bai, Yuxiang Sun, Zhongrui Yan, Wenshi Wei, Jie Chang, Christian Hölscher, Wenxian Du
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:View
Subjects:
GLP‐1RA
neuroinflammation
mitochondrial dysfunction
mitophagy
VaD
Online Access:https://doi.org/10.1002/VIW.20250013
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https://doi.org/10.1002/VIW.20250013

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