Primitive to visceral endoderm maturation is essential for mouse epiblast survival beyond implantation

Summary: The implantation of the mouse blastocyst initiates a complex sequence of tissue remodeling and cell differentiation events required for morphogenesis, during which the extraembryonic primitive endoderm transitions into the visceral endoderm. Through single-cell RNA sequencing of embryos at...

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Bibliographic Details
Main Authors: Antonia Weberling, Dylan Siriwardena, Christopher Penfold, Neophytos Christodoulou, Thorsten E. Boroviak, Magdalena Zernicka-Goetz
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224028980
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