Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens
BK virus is ubiquitously present in the latent state in humans, and awareness of the importance of BK polyomavirus is emerging among the kidney transplant community. First discovered in 1971 in the urine of a renal transplant recipient, BK virus nephropathy (BKVN) has come to be recognized as a sig...
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Format: | Article |
Language: | English |
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Wiley
2006-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1100/tsw.2006.93 |
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author | Christine Wu Parmjeet Randhawa Jerry McCauley |
author_facet | Christine Wu Parmjeet Randhawa Jerry McCauley |
author_sort | Christine Wu |
collection | DOAJ |
description | BK virus is ubiquitously present in the latent state in humans, and awareness of the importance of BK polyomavirus is emerging among the kidney transplant community. First discovered in 1971 in the urine of a renal transplant recipient, BK virus nephropathy (BKVN) has come to be recognized as a significant cause of genitourinary disease and potential graft loss in the kidney transplant patient. In this review, we discuss the risk factors, available methods of diagnosis and therapeutic monitoring, and current approaches to therapy of BKVN. |
format | Article |
id | doaj-art-5cd5c37fe04d4eaeb13bc933a945abdf |
institution | Kabale University |
issn | 1537-744X |
language | English |
publishDate | 2006-01-01 |
publisher | Wiley |
record_format | Article |
series | The Scientific World Journal |
spelling | doaj-art-5cd5c37fe04d4eaeb13bc933a945abdf2025-02-03T06:08:34ZengWileyThe Scientific World Journal1537-744X2006-01-01641252810.1100/tsw.2006.93Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression RegimensChristine Wu0Parmjeet Randhawa1Jerry McCauley2Department of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA, USA2Department of Pathology, Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USADepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA, USABK virus is ubiquitously present in the latent state in humans, and awareness of the importance of BK polyomavirus is emerging among the kidney transplant community. First discovered in 1971 in the urine of a renal transplant recipient, BK virus nephropathy (BKVN) has come to be recognized as a significant cause of genitourinary disease and potential graft loss in the kidney transplant patient. In this review, we discuss the risk factors, available methods of diagnosis and therapeutic monitoring, and current approaches to therapy of BKVN.http://dx.doi.org/10.1100/tsw.2006.93 |
spellingShingle | Christine Wu Parmjeet Randhawa Jerry McCauley Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens The Scientific World Journal |
title | Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens |
title_full | Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens |
title_fullStr | Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens |
title_full_unstemmed | Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens |
title_short | Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens |
title_sort | transplantation polyomavirus nephropathy and the risk of specific immunosuppression regimens |
url | http://dx.doi.org/10.1100/tsw.2006.93 |
work_keys_str_mv | AT christinewu transplantationpolyomavirusnephropathyandtheriskofspecificimmunosuppressionregimens AT parmjeetrandhawa transplantationpolyomavirusnephropathyandtheriskofspecificimmunosuppressionregimens AT jerrymccauley transplantationpolyomavirusnephropathyandtheriskofspecificimmunosuppressionregimens |