Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens

BK virus is ubiquitously present in the latent state in humans, and awareness of the importance of BK polyomavirus is emerging among the kidney transplant community. First discovered in 1971 in the urine of a renal transplant recipient, BK virus nephropathy (BKVN) has come to be recognized as a sig...

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Main Authors: Christine Wu, Parmjeet Randhawa, Jerry McCauley
Format: Article
Language:English
Published: Wiley 2006-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2006.93
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author Christine Wu
Parmjeet Randhawa
Jerry McCauley
author_facet Christine Wu
Parmjeet Randhawa
Jerry McCauley
author_sort Christine Wu
collection DOAJ
description BK virus is ubiquitously present in the latent state in humans, and awareness of the importance of BK polyomavirus is emerging among the kidney transplant community. First discovered in 1971 in the urine of a renal transplant recipient, BK virus nephropathy (BKVN) has come to be recognized as a significant cause of genitourinary disease and potential graft loss in the kidney transplant patient. In this review, we discuss the risk factors, available methods of diagnosis and therapeutic monitoring, and current approaches to therapy of BKVN.
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spelling doaj-art-5cd5c37fe04d4eaeb13bc933a945abdf2025-02-03T06:08:34ZengWileyThe Scientific World Journal1537-744X2006-01-01641252810.1100/tsw.2006.93Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression RegimensChristine Wu0Parmjeet Randhawa1Jerry McCauley2Department of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA, USA2Department of Pathology, Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USADepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA, USABK virus is ubiquitously present in the latent state in humans, and awareness of the importance of BK polyomavirus is emerging among the kidney transplant community. First discovered in 1971 in the urine of a renal transplant recipient, BK virus nephropathy (BKVN) has come to be recognized as a significant cause of genitourinary disease and potential graft loss in the kidney transplant patient. In this review, we discuss the risk factors, available methods of diagnosis and therapeutic monitoring, and current approaches to therapy of BKVN.http://dx.doi.org/10.1100/tsw.2006.93
spellingShingle Christine Wu
Parmjeet Randhawa
Jerry McCauley
Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens
The Scientific World Journal
title Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens
title_full Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens
title_fullStr Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens
title_full_unstemmed Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens
title_short Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens
title_sort transplantation polyomavirus nephropathy and the risk of specific immunosuppression regimens
url http://dx.doi.org/10.1100/tsw.2006.93
work_keys_str_mv AT christinewu transplantationpolyomavirusnephropathyandtheriskofspecificimmunosuppressionregimens
AT parmjeetrandhawa transplantationpolyomavirusnephropathyandtheriskofspecificimmunosuppressionregimens
AT jerrymccauley transplantationpolyomavirusnephropathyandtheriskofspecificimmunosuppressionregimens