Housing Temperature Impacts the Systemic and Tissue‐Specific Molecular Responses to Cancer in Mice

Housing Temperature Impacts the Systemic and Tissue‐Specific Molecular Responses to Cancer in Mice

ABSTRACT Background Cancer cachexia, affecting up to 80% of patients with cancer, is characterized by muscle and fat loss with functional decline. Preclinical research seeks to uncover the molecular mechanisms underlying cachexia to identify potential targets. Housing laboratory mice at ambient temp...

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Main Authors: Andrea Irazoki, Emma Frank, Tang Cam Phung Pham, Jessica L. Braun, Amy M. Ehrlich, Mark Haid, Fabien Riols, Camilla Hartmann Friis Hansen, Anne‐Sofie Rydal Jørgensen, Nicoline Resen Andersen, Laura Hidalgo‐Corbacho, Roberto Meneses‐Valdes, Mona Sadek Ali, Steffen Henning Raun, Johanne Louise Modvig, Samantha Gallero, Steen Larsen, Zach Gerhart‐Hines, Thomas Elbenhardt Jensen, Maria Rohm, Jonas T. Treebak, Val Andrew Fajardo, Lykke Sylow
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
bioenergetics
cancer cachexia
cold‐induced stress
thermogenic tissues
thermoneutrality
Online Access:https://doi.org/10.1002/jcsm.13781
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https://doi.org/10.1002/jcsm.13781

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