Production and analysis of the biological properties of recombinant human granulocyte colony stimulating factor chimeric form

Production and analysis of the biological properties of recombinant human granulocyte colony stimulating factor chimeric form

The aim of this work was to design and study biological properties of the recombinant human granulocyte colony stimulating factor (G-CSF), «linked» to apolipoprotein A-I (apoA-I) by a peptide linker, for obtaining in perspective a prolong form of the drug based on this cytokine.Material and methods....

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Bibliographic Details
Main Authors: M. B. Pykhtina, V. P. Romanov, S. M. Miroshnichenko, A. B. Beklemishev
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Siberian Branch Publishing House 2020-01-01
Series:Сибирский научный медицинский журнал
Subjects:
human g-csf
apoa-i
cloning
chimeric gene
pichia pastoris x-33
ion exchange chromatography
bone marrow cells
flow cytometry
Online Access:https://sibmed.elpub.ru/jour/article/view/310
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https://sibmed.elpub.ru/jour/article/view/310

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