Simultaneous Determination of Unbound Plasma Concentration of Methotrexate and 7-Hydroxymethotrexate in Children Patients Receiving High-Dose Methotrexate Therapy

Wei-Chong Dong,1,2 Shuai-Shuai Gao,1 Bo Shi,3 Hao-Ran Li,1 Ye Jiang,4,5 Jia-Liang Guo,3 Zhi-Qing Zhang,1 Ying-Ze Zhang2,3 1Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, 050051, People’s Republic of China; 2The School of Medicine, Nankai Univer...

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Bibliographic Details
Main Authors: Dong WC, Gao SS, Shi B, Li HR, Jiang Y, Guo JL, Zhang ZQ, Zhang YZ
Format: Article
Language:English
Published: Dove Medical Press 2025-05-01
Series:Drug Design, Development and Therapy
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Online Access:https://www.dovepress.com/simultaneous-determination-of-unbound-plasma-concentration-of-methotre-peer-reviewed-fulltext-article-DDDT
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