基于生物信息学途径评估 UBE2 家族及 UBE2T 基因在肺腺癌中的表达及临床意义
【目的】探究泛素结合酶E2家族和泛素结合酶E2T(UBE2T)在肺腺癌中的表达情况及其与临床病理特征之间的关系。【方法】利用linkedomics平台进行UBE2C、UBE2M、UBE2S、UBE2T、UBE2V2 mRNA表达水平与肺腺癌临床特征之间的关系分析,对总生存时间(OS)(Cox回归检验)、总分期(Kruskal-WallisH检验)、T分期(Kruskal-WallisH检验)、N分期(Kruskal-WallisH检验)及M分期(Wilcox秩和检验)进行差异比较。运用肿瘤基因组图谱(TCGA)数据库获取UBE2T基因在肺腺癌组织和癌旁组织中的表达信息,将结果进行两独立样本t检...
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Main Authors: | 杨豪帅, 赖慧娜, 饶怡茹, 林晓平 |
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Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Sun Yat-sen University
2020-01-01
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Series: | Zhongshan Daxue xuebao. Yixue kexue ban |
Subjects: | |
Online Access: | http://xuebaoyx.sysu.edu.cn/zh/article/43567561/ |
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