Reduced Activity of HDAC3 and Increased Acetylation of Histones H3 in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis

Reduced Activity of HDAC3 and Increased Acetylation of Histones H3 in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis

Aberrant histone acetylation and deacetylation are increasingly thought to play important roles in the pathogenesis of rheumatoid arthritis (RA). However, limited data from studies about the activity of histone deacetylases (HDACs) and histone acetyltransferase (HAT) in RA are controversial. Those c...

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Bibliographic Details
Main Authors: Yan Li, Mi Zhou, Xiuying Lv, Lina Song, Di Zhang, Yan He, Mian Wang, Xue Zhao, Xiaoqing Yuan, Guixiu Shi, Dashan Wang
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2018/7313515
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http://dx.doi.org/10.1155/2018/7313515

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