Fucoxanthin and its metabolite fucoxanthinol alleviate paraquat-induced oxidative damage and neurotoxicity in differentiated human neuroblastoma cells

Fucoxanthin and its metabolite fucoxanthinol alleviate paraquat-induced oxidative damage and neurotoxicity in differentiated human neuroblastoma cells

Paraquat (PQ), a widely used herbicide, is linked to increased Parkinson's disease (PD) risk. This study explored the neuroprotective effects of fucoxanthin (FX) and its metabolite fucoxanthinol (FXL) in a differentiated dopaminergic neuron model. PQ exposure (10 µM) for 72 hours reduced cell v...

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Bibliographic Details
Main Authors: Ekramy M. Elmorsy, Ayat B. Al-Ghafari, Huda A. Al Doghaither, Mohamed M. Salama, Hanaa M. Elzahed, Raed AlRuwaili
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Journal of Taibah University for Science
Subjects:
Fucoxanthin
fucoxanthinol
neurotoxicity
paraquat
pesticides
Online Access:https://www.tandfonline.com/doi/10.1080/16583655.2025.2512661
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https://www.tandfonline.com/doi/10.1080/16583655.2025.2512661

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