Transcriptional and post-transcriptional regulation of CARMN and its anti-tumor function in cervical cancer through autophagic flux blockade and MAPK cascade inhibition

Transcriptional and post-transcriptional regulation of CARMN and its anti-tumor function in cervical cancer through autophagic flux blockade and MAPK cascade inhibition

Abstract Background LncRNAs play essential roles in multiple tumors. However, research on genome-wide lncRNA alterations and their functions in cervical cancer (CC) is limited. This study aims to explore key lncRNAs in CC progression and uncover the molecular mechanisms involved in the development o...

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Main Authors: Xing Zhang, Wenjing Yan, Hua Jin, Bingjia Yu, Hao Zhang, Bo Ding, Xue Chen, Yan Zhang, Qianqian Xia, Dan Meng, Jing Hu, Haohan Liu, Yamei Nie, Fengying Liu, Yun Zheng, Yiran Lu, Juan Wang, Mulong Du, Meilin Wang, Evan Yi-Wen Yu, Xiuting Li, Shizhi Wang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
LncRNA
Cervical cancer
CARMN
Polymorphism
RNA stability
Online Access:https://doi.org/10.1186/s13046-024-03229-y
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https://doi.org/10.1186/s13046-024-03229-y

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