Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway

Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway

Aims: Osteoarthritis (OA) is a common degenerative disease that leads to pain, disability, and reduced quality of life. Orientin exhibits considerable anti-inflammatory and antioxidative properties, but its role in chondrocyte senescence and OA progress has not yet been fully characterized. The aim...

Full description

Saved in:
Bibliographic Details
Main Authors: Haitao Chen, Siyi Liu, Junwei Xing, Yinxian Wen, Liaobin Chen
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2025-03-01
Series:Bone & Joint Research
Subjects:
osteoarthritis
orientin
chondrocyte senescence
reactive oxygen species
pi3k/akt pathway
chondrocytes
osteoarthritis (oa)
rat model
interleukin
osteophytes
cartilage
rna
radiograph
nuclear factor kappa b
anterior cruciate ligament transection (aclt)
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.143.BJR-2023-0383.R2
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.143.BJR-2023-0383.R2

Similar Items