Identification and validation of pyroptosis patterns in AML via comprehensive bioinformatics analysis
Abstract Pyroptosis, a lytic inflammatory cell death mechanism, plays dual roles in tumorigenesis, but its clinical relevance in acute myeloid leukemia (AML) remains poorly understood. Through an integrative analysis of 40 pyroptosis-related genes in newly diagnosed AML patients (TCGA, n = 151) and...
Saved in:
| Main Authors: | Zeyu Deng, Hongkai Zhu, Zhao Cheng, Ruijuan Li, Hongling Peng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-04-01
|
| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02298-5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Integrated bioinformatics and functional studies identify CDK9 as a potential prognostic biomarker and therapeutic target in AML
by: Zhibin Xie, et al.
Published: (2025-06-01) -
Essential thrombocytosis transformed AML with TP53 mutations and its clinical implications
by: Yang Si, et al.
Published: (2024-12-01) -
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
by: Yang Song, et al.
Published: (2025-06-01) -
FGFC1 overcomes Ara-C resistance in acute myeloid leukemia by inducing apoptosis and pyroptosis
by: Xiaohui Hu, et al.
Published: (2025-08-01) -
5-FU@HFn combined with decitabine induces pyroptosis and enhances antitumor immunotherapy for chronic myeloid leukemia
by: Zuowei Yuan, et al.
Published: (2025-03-01)