Identification and validation of pyroptosis patterns in AML via comprehensive bioinformatics analysis

Abstract Pyroptosis, a lytic inflammatory cell death mechanism, plays dual roles in tumorigenesis, but its clinical relevance in acute myeloid leukemia (AML) remains poorly understood. Through an integrative analysis of 40 pyroptosis-related genes in newly diagnosed AML patients (TCGA, n = 151) and...

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Bibliographic Details
Main Authors: Zeyu Deng, Hongkai Zhu, Zhao Cheng, Ruijuan Li, Hongling Peng
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-02298-5
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