Aspartyl protease inhibition interferes with Plasmodium falciparum asexual blood-stage and early gametocyte development

Abstract Background Plasmodium falciparum is the most influential species of malaria parasites, capable of causing severe illness and mortality, especially in pregnant women and children under the age of 5. Global distribution of disease impacted on billions of endemic people and travellers. Asexual...

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Main Authors: Gamolthip Niramolyanun, Chonnipa Praikongkatham, Rachaneeporn Jenwithisuk, Wanlapa Roobsoong, Jetsumon Sattabongkot, Viriya Pankao, Niwat Kangwanrangsan
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Malaria Journal
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Online Access:https://doi.org/10.1186/s12936-025-05518-z
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