Metabolic consequences of altered kidney glucose reabsorption under normoglycemic conditions

Metabolic consequences of altered kidney glucose reabsorption under normoglycemic conditions

Objective: Kidney glucose reabsorption, primarily mediated by glucose transporter 2 (GLUT2), is essential for systemic glucose homeostasis. While GLUT2's role has been studied in diabetic conditions, its function in kidney proximal tubule cells (KPTCs) under normo-physiological conditions remai...

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Main Authors: Majdoleen Ahmad, Anna Permyakova, Saja Baraghithy, Nilanjan Sahu, Ifat Abramovich, Bella Agranovich, Ori Shalev, Aviram Kogot-Levin, Alina Nemirovski, Eyal Gottlieb, Rinat Abramovitch, Gil Leibowitz, Liad Hinden, Joseph Tam
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Molecular Metabolism
Subjects:
Kidney glucose reabsorption
KPTCs
Energy metabolism
GLUT2
Taurine
Creatine
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825000997
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