In-depth characterization of Klebsiella pneumoniae carbapenemase (KPC)-encoding plasmids points at transposon-related transmission of resistance genes

In-depth characterization of Klebsiella pneumoniae carbapenemase (KPC)-encoding plasmids points at transposon-related transmission of resistance genes

Antimicrobial resistance (AMR) is a growing threat in healthcare systems, particularly in the management of infections in critically ill patients. This study highlights how to identify clusters and putative sharing of mobile genetic elements, such as transposons, in the hospital setting using long-r...

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Bibliographic Details
Main Authors: Vincent F. van Almsick, Annika Sobkowiak, Natalie Scherff, Franziska Schuler, Johannes Benedict Oehm, Christian Böing, Alexander Mellmann, Vera Schwierzeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
antimicrobial resistance
KPC-3
long-read whole genome sequencing
Klebsiella pneumoniae
hospital transmission
transposon
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1542828/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1542828/full

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