Sex-differentiated placental methylation and gene expression regulation has implications for neonatal traits and adult diseases
Abstract Sex differences in physiological and disease traits are pervasive and begin during early development, but the genetic architecture of these differences is largely unknown. Here, we leverage the human placenta, a transient organ during pregnancy critical to fetal development, to investigate...
Saved in:
| Main Authors: | Fasil Tekola-Ayele, Richard J. Biedrzycki, Tesfa Dejenie Habtewold, Prabhavi Wijesiriwardhana, Amber Burt, Carmen J. Marsit, Marion Ouidir, Ronald Wapner |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-58128-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Longitudinal maternal glycemia during pregnancy and placental epigenetic age acceleration
by: Tesfa Dejenie Habtewold, et al.
Published: (2025-02-01) -
Maternal parity modifies the association of birthweight polygenic score with fetal growth
by: Prabhavi Wijesiriwardhana, et al.
Published: (2025-07-01) -
Assessment of Prevalence and Determinants of Occupational Exposure to HIV Infection among Healthcare Workers in Selected Health Institutions in Debre Berhan Town, North Shoa Zone, Amhara Region, Ethiopia, 2014
by: Filmawit Aynalem Tesfay, et al.
Published: (2014-01-01) -
Placental 11-beta hydroxysteroid dehydrogenase methylation is associated with newborn growth and a measure of neurobehavioral outcome.
by: Carmen J Marsit, et al.
Published: (2012-01-01) -
Potentially causal associations between placental DNA methylation and schizophrenia and other neuropsychiatric disorders
by: Ariadna Cilleros-Portet, et al.
Published: (2025-03-01)