Immunoreactivity Analysis of MHC-I Epitopes Derived from the Nucleocapsid Protein of SARS-CoV-2 via Computation and Vaccination

Immunoreactivity Analysis of MHC-I Epitopes Derived from the Nucleocapsid Protein of SARS-CoV-2 via Computation and Vaccination

<b>Background</b>: Since 2019, the SARS-CoV-2 virus has been responsible for the global spread of respiratory illness. As of 1 September 2024, the cumulative number of infections worldwide exceeded 776 million. There are many structural proteins of the virus, among which the SARS-CoV-2 n...

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Main Authors: Dongbo Jiang, Zilu Ma, Junqi Zhang, Yubo Sun, Tianyuan Bai, Ruibo Liu, Yongkai Wang, Liang Guan, Shuaishuai Fu, Yuanjie Sun, Yuanzhe Li, Bingquan Zhou, Yulin Yang, Shuya Yang, Yuanhang Chang, Baozeng Sun, Kun Yang
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Vaccines
Subjects:
SARS-CoV-2
nucleocapsid protein (NP)
MHC-I-restricted epitopes
CD8+ T cell response
immunogenicity
Online Access:https://www.mdpi.com/2076-393X/12/11/1214
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