Gpr37 modulates the severity of inflammation-induced GI dysmotility by regulating enteric reactive gliosis

Gpr37 modulates the severity of inflammation-induced GI dysmotility by regulating enteric reactive gliosis

Summary: The enteric nervous system (ENS) is contained within two layers of the gut wall and is made up of neurons and enteric glial cells (EGCs) that regulate gastrointestinal (GI) function. EGCs in both inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) change in response to infla...

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Main Authors: Keiramarie Robertson, Oliver Hahn, Adarsh Tantry, Beatriz G. Robinson, Arwa T. Faruk, Mathangi Janakiraman, Hong Namkoong, Kwangkon Kim, Jiayu Ye, Estelle Spear Bishop, Randy A. Hall, Tony Wyss-Coray, Laren Becker, Julia A. Kaltschmidt
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:iScience
Subjects:
Neuroscience
Molecular biology
Immunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225011460
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http://www.sciencedirect.com/science/article/pii/S2589004225011460

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