Aqueous and Ethanol Extracts of Acacia sieberiana (Fabaceae) Stem Bark Reverse the Pain–Depression Dyad in Mice Through Modulation of Catecholamines, Proinflammatory Cytokines, and Oxidative Stress

Conclusion: AE and EE are effective against pain and depression. Their pharmacological activities might be related to the modulation of inflammation, oxidative stress and catecholamine, and the presence of bioactive natural products.

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Bibliographic Details
Main Authors: Sorelle Ngassam Mbankou, Aliance Romain Fokoua, Cedric Wamba Koho, Roger Hermann Sadie Foguieng, Sahar Mofidi Tabatabaei, Pamela Arielle Nono Nankam, Kevin Joseph Tidgewell, Télesphore Benoît Nguelefack
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advances in Pharmacological and Pharmaceutical Sciences
Online Access:http://dx.doi.org/10.1155/adpp/1244498
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