Lactate and lactylation: novel perspectives on fibrosis pathogenesis and therapeutic directions

Abstract Fibrosis is the common terminal pathway of abnormal tissue repair in various chronic diseases and has become a major global health challenge. Recent research has identified metabolic reprogramming as one of the key factors in the pathogenesis of fibrosis. Lactate, once considered a simple b...

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Bibliographic Details
Main Authors: Huanwei Liang, Linlin Xu, Yi Yang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06748-0
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