An extracellular vesicle based hypothesis for the genesis of the polycystic kidney diseases

Autosomal dominant polycystic kidney (ADPKD) disease is the commonest genetic cause of kidney failure (affecting 1:800 individuals) and is due to heterozygous germline mutations in either of two genes, PKD1 and PKD2. Homozygous germline mutations in PKHD1 are responsible for autosomal recessive poly...

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Bibliographic Details
Main Authors: Marie C. Hogan, Christopher J. Ward
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Extracellular Vesicle
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2773041724000155
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